Maria is a powerful young witch living with her two familiars in medieval France during the Hundred Years' War against England. As the war rages on and the innocent get caught in its destruction, Maria becomes fed up with the situation and begins using her magic to try and prevent further conflict in hopes of maintaining peace. However, her constant intervention soon attracts the attention of the heavens, and the archangel Michael is sent to keep her from meddling in human affairs. The divine being confronts Maria, and he forbids her from using her powers, issuing a decree that her magic will be taken if she loses her virginity. Though she is now labeled a heretic, Maria adamantly refuses to heed Michael's warning and continues to disrupt the war between the two nations. But as the Church begins plotting to take away the witch's power and put a stop to Maria's interference once and for all, her peacemaking may soon come to an end. [Written by MAL Rewrite]

When Yumi Fukuzawa entered the Lillian Girls' Academy, a prestigious all-girls Catholic school in Tokyo, she never imagined she would catch the eye of beautiful and demure Sachiko Ogasawara, one of the school's most popular students. Now Sachiko has offered to be Yumi's soeur, her "sister" and guide for all her years at the academy. The whole idea has Yumi completely flustered—after all, they hardly know each other! The entire campus is abuzz with rumors about the two of them, but Yumi is conflicted over accepting Sachiko's offer. While she admires Sachiko, being her soeur would also mean constantly being at the center of the entire school's attention!

Summer has arrived, and the students of Lillian Girls' Academy are on break! Yumi and Sachiko head out to the Ogasawara family's summer home, but what was supposed to be a relaxing vacation takes a turn for the worse when some of Sachiko's old acquaintances drop by for tea. These rich and snobby debutantes don't think Yumi is worthy of Sachiko's affection and they're out to make this summer one she'll regret.

A series of chibi-style "outtakes" from the "shooting" of the Mariamite series.

Life goes on for the ladies in the Yamayurikai. On the one-year anniversary of Sachiko and Yumi becoming sisters, Yumi receives a difficult task from Sachiko: to finally acknowledge someone as her younger sister.  

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A series of specials included on the Maria-sama ga Miteru DVD releases.

Specials of Maria-sama ga Miteru: Haru released on the DVDs only.

 Marika is an ordinary, gothic lolita middle schooler. However, with only the slightest mention of science, she begins to get sleepy. One day while riding the train, her handmade stuffed animal “Pet” begins to move on its own. To make matters worse, she ends up in a strange town she’s never heard of known as Galihabara. Here, Marika encounters the astronomer Galileo, as well as a number of history’s other greatest scientists. However, they’re all a little different here…

Marika is an ordinary, gothic lolita middle schooler. However, with only the slightest mention of science, she begins to get sleepy. One day while riding the train, her handmade stuffed animal “Pet” begins to move on its own. To make matters worse, she ends up in a strange town she’s never heard of known as Galihabara. Here, Marika encounters the astronomer Galileo, as well as a number of history’s other greatest scientists. However, they’re all a little different here…

The second season of Marie & Gali.

The story of the manga centers around Marimo Nogami, a usually quiet fourth-grade girl in elementary school. However, a certain incident leads to Marimo's personal strength blossoming.